Molecular Targeted Therapy

siRNA Nanoparticle Functionalization of Nanostructured Scaffolds Enables Controlled Multilineage Differentiation of Stem Cells

Technology / Tissue Engineering / Flow Cytometry / Nanoparticles / Stem Cell / Apoptosis / Gene Silencing / Western blotting / Biological Sciences / Molecular / Cell Differentiation / Humans / Mice / Female / Animals / Nanostructures / Mesenchymal Stem Cell / Adipocytes / Chondrogenesis / Cell Proliferation / Osteoblasts / DNA binding proteins / Molecular Targeted Therapy / Mesenchymal Stromal Cells / Apoptosis / Gene Silencing / Western blotting / Biological Sciences / Molecular / Cell Differentiation / Humans / Mice / Female / Animals / Nanostructures / Mesenchymal Stem Cell / Adipocytes / Chondrogenesis / Cell Proliferation / Osteoblasts / DNA binding proteins / Molecular Targeted Therapy / Mesenchymal Stromal Cells

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ADAM8 as a drug target in pancreatic cancer

Membrane Proteins / Multidisciplinary / Western blotting / Signal Transduction / Humans / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase

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Probing In Vivo Trafficking of Polymer/DNA Micellar Nanoparticles Using SPECT/CT Imaging

Technology / Computed Tomography / Kinetics / Nanoparticles / Biological Sciences / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis

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Tissue transglutaminase: a new target to reverse cancer drug resistance

Enzyme Inhibitors / Humans / Animals / Amino Acids / Neoplasms / Antineoplastic Agents / Molecular Targeted Therapy / Transglutaminases / Antineoplastic Agents / Molecular Targeted Therapy / Transglutaminases

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ADAM8 as a drug target in pancreatic cancer

Membrane Proteins / Multidisciplinary / Western blotting / Signal Transduction / Humans / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase / Mice / Animals / Cyclic peptides / Phosphorylation / Neoplasm Invasiveness / Protein Binding / Hydroxamic Acids / Molecular Targeted Therapy / Nature Communications / Extracellular Space / Matrix Metalloproteinase

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Microvesicle-associated AAV Vector as a Novel Gene Delivery System

Technology / Electron Microscopy / Biological Sciences / Molecular / Humans / Gene transfer techniques / Capsid / Neoplasms / Transfection / Molecular Targeted Therapy / Gene transfer techniques / Capsid / Neoplasms / Transfection / Molecular Targeted Therapy

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Probing In Vivo Trafficking of Polymer/DNA Micellar Nanoparticles Using SPECT/CT Imaging

Technology / Computed Tomography / Kinetics / Nanoparticles / Biological Sciences / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis

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Microvesicle-associated AAV Vector as a Novel Gene Delivery System

Technology / Electron Microscopy / Biological Sciences / Molecular / Humans / Gene transfer techniques / Capsid / Neoplasms / Transfection / Molecular Targeted Therapy / Gene transfer techniques / Capsid / Neoplasms / Transfection / Molecular Targeted Therapy

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844. A Single Vector-Dependent, Doxycycline Regulatable, Lung Cancer Specific Oncolytic Adenovirus

Technology / Biological Sciences / Lung Cancer / Molecular Targeted Therapy

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Age-specific transcriptional response to stroke

Aging / Cell Cycle / Inflammation / Oxidative Stress / DNA repair / Stroke / Brain / Humans / Mice / Animals / Male / Neuronal Plasticity / Depressive Disorder / Risk factors / Nerve Regeneration / Clinical Sciences / SYNAPSES / Risk Factors / Neurobiology of Aging / Molecular Targeted Therapy / Neurosciences / Stroke / Brain / Humans / Mice / Animals / Male / Neuronal Plasticity / Depressive Disorder / Risk factors / Nerve Regeneration / Clinical Sciences / SYNAPSES / Risk Factors / Neurobiology of Aging / Molecular Targeted Therapy / Neurosciences

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Maraba Virus as a Potent Oncolytic Vaccine Vector

Technology / Treatment Outcome / Gene expression / Cancer Vaccines / Biological Sciences / Mice / Female / Animals / Oncolytic Viruses / Neoplasms / Molecular Targeted Therapy / Mice / Female / Animals / Oncolytic Viruses / Neoplasms / Molecular Targeted Therapy

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Preclinical Corrective Gene Transfer in Xeroderma Pigmentosum Human Skin Stem Cells

Genetics / Technology / Stem Cells / Flow Cytometry / Gene Therapy / Human Skin Ageing / Stem Cell / Western blotting / Biological Sciences / Molecular / Humans / Keratinocytes / Skin Cancer / Ultraviolet / Skin / Nucleotide Excision Repair / Epidermis / Murine Model / DNA binding proteins / Molecular Targeted Therapy / Xeroderma Pigmentosum / Gene Transfer / Human Skin Ageing / Stem Cell / Western blotting / Biological Sciences / Molecular / Humans / Keratinocytes / Skin Cancer / Ultraviolet / Skin / Nucleotide Excision Repair / Epidermis / Murine Model / DNA binding proteins / Molecular Targeted Therapy / Xeroderma Pigmentosum / Gene Transfer

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Probing In Vivo Trafficking of Polymer/DNA Micellar Nanoparticles Using SPECT/CT Imaging

Technology / Computed Tomography / Kinetics / Nanoparticles / Biological Sciences / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis / DNA / Molecular / Micelles / Liver / Female / Animals / Gene transfer techniques / Plasmids / Gene Delivery / Polyethylene Glycol / Rats / Single Photon Emission Computed Tomography / Wistar Rats / Molecular Targeted Therapy / Physicochemical Properties / Polyethylene Glycols / Quantitative Image Analysis

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GPR119 as a fat sensor

Biological Sciences / Humans / Mice / G protein-coupled receptors / Animals / Drug Design / Oral Hypoglycemic Agents / Type 2 Diabetes Mellitus / Trends In Pharmacological Sciences / Molecular Targeted Therapy / Drug Design / Oral Hypoglycemic Agents / Type 2 Diabetes Mellitus / Trends In Pharmacological Sciences / Molecular Targeted Therapy

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553. A Potent Replicative Delta Adenoviral Vector for HPV Tumors

Technology / DNA replication / Public Health / Biological Sciences / Molecular / HUMAN PAPILLOMAVIRUS / Cell line / Molecular Targeted Therapy / Tissue Specificity / Quantitative polymerase chain reaction / HUMAN PAPILLOMAVIRUS / Cell line / Molecular Targeted Therapy / Tissue Specificity / Quantitative polymerase chain reaction

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Mesoporous silica nanoparticles as a drug delivery system

Technology / Targeted Drug Delivery / Nanoparticles / Drug Delivery System / Stem Cell / Signal Transduction / Biological Sciences / Molecular / Cell line / Humans / Porosity / Mice / Silica / Female / Animals / Drug Delivery Systems / Targeted Therapy / Side Effect / Silicon Dioxide / Antineoplastic Agents / Molecular Targeted Therapy / Clinical Application / Anticancer Drug / Signal Transduction / Biological Sciences / Molecular / Cell line / Humans / Porosity / Mice / Silica / Female / Animals / Drug Delivery Systems / Targeted Therapy / Side Effect / Silicon Dioxide / Antineoplastic Agents / Molecular Targeted Therapy / Clinical Application / Anticancer Drug

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